CONTENTS

Front Matter

Title Page, Preface and Acknowledgements
About the Author
Status, History, Issues and Updates
Complementary Textbooks
Teaching Notes and Resources
A Note about Numerical Solutions

Course Units

I. Chemical Reactions
1. Stoichiometry and Reaction Progress
2. Reaction Thermochemistry
3. Reaction Equilibrium
II. Chemical Reaction Kinetics
A. Rate Expressions
4. Reaction Rates and Temperature Effects
5. Empirical and Theoretical Rate Expressions
6. Reaction Mechanisms
7. The Steady State Approximation
8. Rate-Determining Step
9. Homogeneous and Enzymatic Catalysis
10. Heterogeneous Catalysis
B. Kinetics Experiments
11. Laboratory Reactors
12. Performing Kinetics Experiments
C. Analysis of Kinetics Data
13. CSTR Data Analysis
14. Differential Data Analysis
15. Integral Data Analysis
16. Numerical Data Analysis
III. Chemical Reaction Engineering
A. Ideal Reactors
17. Reactor Models and Reaction Types
B. Perfectly Mixed Batch Reactors
18. Reaction Engineering of Batch Reactors
19. Analysis of Batch Reactors
20. Optimization of Batch Reactor Processes
C. Continuous Flow Stirred Tank Reactors
21. Reaction Engineering of CSTRs
22. Analysis of Steady State CSTRs
23. Analysis of Transient CSTRs
24. Multiple Steady States in CSTRs
D. Plug Flow Reactors
25. Reaction Engineering of PFRs
26. Analysis of Steady State PFRs
27. Analysis of Transient PFRs
E. Matching Reactors to Reactions
28. Choosing a Reactor Type
29. Multiple Reactor Networks
30. Thermal Back-Mixing in a PFR
31. Back-Mixing in a PFR via Recycle
32. Ideal Semi-Batch Reactors
IV. Non-Ideal Reactions and Reactors
A. Alternatives to the Ideal Reactor Models
33. Axial Dispersion Model
34. 2-D and 3-D Tubular Reactor Models
35. Zoned Reactor Models
36. Segregated Flow Models
37. Overview of Multi-Phase Reactors
B. Coupled Chemical and Physical Kinetics
38. Heterogeneous Catalytic Reactions
39. Gas-Liquid Reactions
40. Gas-Solid Reactions

Supplemental Units

S1. Identifying Independent Reactions
S2. Solving Non-differential Equations
S3. Fitting Linear Models to Data
S4. Numerically Fitting Models to Data
S5. Solving Initial Value Differential Equations
S6. Solving Boundary Value Differential Equations

Complementary Textbooks

There are many, many good textbooks available on the topics of Kinetics and Reaction Engineering. Here are a few that you may find useful, including a few that are more specifically focused on biological or biochemical kinetics and reaction engineering.


Aiba, S., Humphrey, A. E. and Millis, N. F., “Biochemical Engineering,” Second Ed., Academic, New York (1973).

Aris, R., “Elementary Chemical Reactor Analysis,” Butterworth, Toronto (1989).

Bailey, J. E., Ollis, D. F. and Bailey, J., “Biochemical Engineering Fundamentals,” Second Ed., McGraw-Hill, New York (1986).

Benson, S. W., “The Foundations of Chemical Kinetics,” Robert E. Krieger, Malabar, FL (1982).

Blanch, H. W. and Clark, D. S., “Biochemical Engineering,” Marcel Dekker, New York (1996).

Boudart, M., “Kinetics of Chemical Processes,” Butterworth-Heinemann, (1991).

Davis, M. E. and Davis, R. J., “Fundamentals of Chemical Reaction Engineering,” McGraw-Hill, New York (2003).

Fogler, H. S., “Elements of Chemical Reaction Engineering,” 3rd ed., Prentice Hall, Upper Saddle River, N.J. (1999).

Froment, G. F. and Bischoff, K. B., “Chemical Reactor Analysis and Design,” Wiley, New York (1990).

Hill, C. G., “An Introduction to Chemical Engineering Kinetics & Reactor Design,” Wiley, New York (1977).

Holland, C. D. and Anthony, R. G., “Fundamentals of Chemical Reaction Engineering,” Prentice Hall, Engelwood Cliffs, NJ (1989).

House, J. E., “Principles of Chemical Kinetics,” Academic, New York (2007).

Laidler, K. J., “Chemical Kinetics,” McGraw-Hill, New York (1965).

Levenspiel, O., “Chemical Reaction Engineering,” Wiley, New York (1972).

Masel, R. I., “Chemical Kinetics and Catalysis,” Wiley, New York (2001).

Missen, R. W., Mims, C. A., and Saville, B. A., “Introduction to Chemical Reaction Engineering and Kinetics,” Wiley, New York (1999).

Nauman, E. B., “Chemical Reactor Design,” Wiley, New York (1987).

Roberts, G. W., “Chemical Reactions and Chemical Reactors,” Wiley, New York (2009).

Schmidt, L. D., “The Engineering of Chemical Reactions,” Oxford, New York (1998).

Shuler, M. L. and Kargi, F., “Bioprocess Engineering: Basic Concepts,” Second Ed., Prentice Hall, Upper Saddle River, NJ (2001).

Smith, J. M., “Chemical Engineering Kinetics,” McGraw-Hill, New York (1970).

Steinfeld, J. I., Francisco, J. S., and Hase, W. L., “Chemical Kinetics and Dynamics,” Second ed., Prentice Hall, Upper Saddle River, NJ (1999).

Stephanopoulos, G., Aristidou, A. and Nielsen, J., “Metabolic Engineering: Principles and Methodologies,” Academic, New York (1998).

Walas, S. M., “Reaction Kinetics for Chemical Engineers,” Butterworths, Toronto (1989).